Multiple Sclerosis: Complete Literature Review and Appended Hypothesis by Alex Dunedin

This is a complete manuscript created over several years investigating the medicine and science of Multiple Sclerosis.  It forms a literature review which has been arranged and where a particular line of thought has been drawn out to form a hypothesis.  Trying to answer the questions of just what ‘Multiple Sclerosis’ is and what causes it led me to seeing a pattern of events which seemed to make sense in context with all the information which I had read.  Read more…

A Study of Multiple Sclerosis: Treatments by Alex Dunedin

Therapies for multiple sclerosis have emerged over the last decades with the demonstration of efficacy of immunomodulating therapies that impact the course of early multiple sclerosis;  Immunosuppressive drugs such as mitoxantrone and cyclophosphamide; Beta-interferons; an MHC-binding protein that engages the T Cell Receptor (TCR), and glatiramer acetate (GA) are all such a class of therapy [12].
Since the market is split between drugs, there has been intense marketing for market share by pharmaceutical companies.  Much impetus has focused on companies competing to position a superior product.  Marketing devices have taken many forms including physician and lay advocates, advertising, educational programs and postmarketing studies.  There has been an array of claims and counterclaims as exchange [78]. Read more…

A Study of Multiple Sclerosis: A Bibliography by Alex Dunedin

This is the bibliography to the complete study of multiple sclerosis which is being published on the Ragged University website over time.

The information resources listed below have been used to create the study and should be consulted in their original texts and compared to get a deeper perspective of the medicine. This bibliography is for reference and where possible digital links have been made out to the source texts to make the forensic task easier. You can find the full written thesis here: Multiple Sclerosis A Hypothesis

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It All Starts With A Thought by Joel White

Every single day of our lives we have thoughts. They are almost a fundamental part of every single human individual. On average, research suggests that we have up to 50,000 to 70,000 thoughts per day (which is roughly 35 to 48 thoughts per minute). Even as you start to read this article you may having a number of multiple thoughts that seem to be happening all at the same time, or even continuously one after another.
The thoughts we have can be idea-like, memory-like, picture-like, or song-like. They also tend not to last. They also seem to be a constant stream and at times they seem to go quiet and something that you were not even thinking about just randomly pops into your head that you were not even consciously thinking about at given moment in time. Read more…