This is a thesis examining bronchial asthma and allergic conditions (Type 1 Hypersensitivity) postulating them as a result of a deficiency of the enzyme lipoprotein lipase and glucuronidation which functions in phase II detoxification processes. Structured and laid out as an example of a concorded hypothesis for the purposes of examining methodologies in the the sciences and knowledge production, the document is designed to provoke and facilitate discussion on the formation of hypotheses. In this case the content of the thesis is almost beside the point.  The question of how we build and document understandings so that arguments may be discussable, accountable and testable is of greater interest. Read more…